BUY NAUSICALM / MARZINE ONLINE and shipping is free

Pack Size

NAUSICALM / MARZINE contains 10 tablets

NAUSICALM / MARZINE Product Information

This medicine is classified as a "Pharmacy Only Medicine" in New Zealand

Cyclizine is a histamine H₁ receptor antagonist of the piperazine class which is characterised by a low incidence of drowsiness. It possesses anticholinergic and antiemetic properties. The exact mechanism by which cyclizine can prevent or suppress both nausea and vomiting from various causes is unknown. Cyclizine increases lower oesophageal sphincter tone and reduces the sensitivity of the labyrinthine apparatus. It may inhibit the part of the midbrain known collectively as the emetic centre.

Active Ingredients

Each NAUSICALM / MARZINE tablet contains 50mg of Cyclizine Hydrochloride

Purpose

NAUSICALM / MARZINE is indicated for the prevention and treatment of nausea and vomiting including:-

• motion sickness when the oral route cannot be used;
• nausea and vomiting caused by narcotic analgesics and by general anaesthetics in the post-operative period;
• vomiting associated with radiotherapy especially for breast cancer since cyclizine does not elevate prolactin levels.

NAUSICALM / MARZINE may be of value in relieving vomiting and attacks of vertigo associated with Menière's disease and other forms of vestibular disturbance when the oral route cannot be used.

 

NAUSICALM / MARZINE Dosage

 

Dose: May be taken with or without food. May repeat dose every 6-8 hours.
Patients > 12 years: 50 mg; max. 150 mg/day.
Children 6-12 years: 25 mg; max. 75 mg/day.
Travel sickness: take 30 minutes before travel.

 

Adverse Reactions

 

Drowsiness, dryness of the mouth, nose and throat, blurred vision, tachycardia, urinary retention, constipation, restlessness, nervousness, insomnia and auditory and visual hallucinations have been reported, particularly when dosage recommendations have been exceeded.

Following oral administration, single case reports have been documented of:-

• fixed drug eruption;
• generalised chorea;
• hypersensitivity hepatitis;
• agranulocytosis.

NAUSICALM / MARZINE may have additive effects with alcohol and other central nervous system depressants (e.g. hypnotics, tranquillizers).

Because of its anticholinergic activity cyclizine may enhance the side- effects of other anticholinergic agents.

In some countries the availability of NAUSICALM / MARZINE as an over the counter sale has led to the misuse of cyclizine, predominantly by teenagers. The aim of abusers is to produce a state of disoriented exhilaration associated with hallucinations. Misuse may be by the oral or intravenous route. The concomitant misuse of NAUSICALM / MARZINE with large amounts of alcohol is particularly dangerous, since the anti-emetic effect of cyclizine may increase the toxicity of alcohol

Note

NAUSICALM / MARZINE sales are restricted to TWO packs (total of 20 tablets)  

Consult the Pharmacist about NAUSICALM / MARZINE online at info@apothecary.co.nz